BDBM96677 3-[(Z)-2-(2-amino-4-methylpyrimidin-5-yl)-2-fluoroethenyl]-4-fluoro-N-[(1S,2S)-2-hydroxycyclohexyl]benzamide::US12509424, Example 204

SMILES Cc1nc(N)ncc1/C(F)=C/c1cc(C(=O)N[C@H]2CCCC[C@@H]2O)ccc1F

InChI Key InChIKey=WMZWOJHNTVQPMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96677   

TargetPlatelet-derived growth factor subunit B(Human)
Nippon Shinyaku Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 96677BDBM96677(3-[(Z)-2-(2-amino-4-methylpyrimidin-5-yl)-2-fluoro...)
Affinity DataIC50: 21nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent