BDBM96685 2-(2-hydroxypropan-2-yl)-N-(4-methyl-3-(2-(5-(pyrazin-2-ylamino)-1H-pyrazol-3-yl)ethyl)phenyl)isonicotinamide::US12509446, Compound 5

SMILES Cc1ccc(NC(=O)c2ccnc(C(C)(C)O)c2)cc1CCc1cc(Nc2cnccn2)[nH]n1

InChI Key InChIKey=YDNHAHAXIKZEOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 96685   

TargetTyrosine-protein kinase Fyn(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96685BDBM96685(2-(2-hydroxypropan-2-yl)-N-(4-methyl-3-(2-(5-(pyra...)
Affinity DataIC50: 6nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96685BDBM96685(2-(2-hydroxypropan-2-yl)-N-(4-methyl-3-(2-(5-(pyra...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent