BDBM96695 N-(3-(2-(5-((3,5-dimethylpyrazin-2-yl)amino)-1H-pyrazol-3-yl)ethyl)-4-fluorophenyl)-3-(trifluoromethyl)benzamide::US12509446, Compound 14

SMILES Cc1cnc(Nc2cc(CCc3cc(NC(=O)c4cccc(C(F)(F)F)c4)ccc3F)n[nH]2)c(C)n1

InChI Key InChIKey=BKJGGCGVBGNJTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 96695   

TargetVascular endothelial growth factor receptor 2(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96695BDBM96695(N-(3-(2-(5-((3,5-dimethylpyrazin-2-yl)amino)-1H-py...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Fyn(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96695BDBM96695(N-(3-(2-(5-((3,5-dimethylpyrazin-2-yl)amino)-1H-py...)
Affinity DataIC50: 31nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent