BDBM96913 3-((1R,6S)-3-oxabicyclo[4.1.0]heptan-6- yl)-N-(5-((4-chlorobenzyl)oxy)-1,3,4- thiadiazol-2-yl)isonicotinamide::US12509454, Compound 175

SMILES O=C(NC1NN=C(OCc2ccc(Cl)cc2)S1)c1ccncc1[C@@]12CCOC[C@@H]1C2

InChI Key InChIKey=OLOSBCQNKSUFHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96913   

TargetDNA polymerase theta [1-899](Human)
Ideaya Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 96913BDBM96913(3-((1R,6S)-3-oxabicyclo[4.1.0]heptan-6- yl)-N-(5-(...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent