BDBM96953 N-(5-((5-cyclopropylpyridin-2- yl)methoxy)-1,3,4-thiadiazol-2-yl)-4-(2- methoxyphenyl)-6-methylnicolinamide::US12509454, Compound 214

SMILES COc1ccccc1-c1cc(C)ncc1C(=O)Nc1nnc(OCc2ccc(C3CC3)cn2)s1

InChI Key InChIKey=HTUHOWGWZNJHAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96953   

TargetDNA polymerase theta [1-899](Human)
Ideaya Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 96953BDBM96953(N-(5-((5-cyclopropylpyridin-2- yl)methoxy)-1,3,4-t...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent