BDBM96965 N-[5-[(5-chloropyridin-2-yl)methoxy]- 1,3,4-thiadiazol-2-yl]-7-(2- methoxyphenyl)imidazo[1,5-a]pyridine-6- carboxamide::US12509454, Compound 224

SMILES COc1ccccc1-c1cc2cncn2cc1C(=O)Nc1nnc(OCc2ccc(Cl)cn2)s1

InChI Key InChIKey=AVKNHBKZZAXUMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 96965   

TargetDNA polymerase theta [1-899](Human)
Ideaya Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 96965BDBM96965(N-[5-[(5-chloropyridin-2-yl)methoxy]- 1,3,4-thiadi...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent