BDBM97106 3-(1'-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)-3- methoxyphenyl)piperidin-4-yl)methyl)-6- oxo-6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A135

SMILES COc1cc(N2CCC(CN3CCC4(CC3)COc3c4ccc4c3CN(C3CCC(=O)NC3=O)C4=O)CC2)ccc1[C@H]1c2ccc(O)cc2OC[C@H]1c1ccccc1

InChI Key InChIKey=HWCRAIQSYXFHSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97106   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97106BDBM97106(3-(1'-((1-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4...)
Affinity DataIC50: 50nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent