BDBM97108 3-(1'-((8-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A137

SMILES O=C1CCC(N2Cc3ccc4c(c3C2=O)OCC42CCN(CC3COC4(CCN(c5ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc5)CC4)C3)CC2)C(=O)N1

InChI Key InChIKey=QCJKIAQNQAZEPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97108   

TargetSteroid hormone receptor ERR1 LBD(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97108BDBM97108(3-(1'-((8-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4...)
Affinity DataIC50: 5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97108BDBM97108(3-(1'-((8-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4...)
Affinity DataIC50: 50nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent