BDBM97124 (R)-3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)-6-oxo- 6,8-dihydro-2H,7H-spiro[furo[2,3- e]isoindole-3,4'-piperidin]-7-yl)piperidine- 2,6-dione::US20260000676, Compound A154

SMILES O=C1CC[C@@H](N2Cc3c(ccc4c3OCC43CCN(CC4CCC5(CC4)CN(c4ccc([C@H]6c7ccc(O)cc7OC[C@H]6c6ccccc6)cc4)C5)CC3)C2=O)C(=O)N1

InChI Key InChIKey=BPZMDXPICADHQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97124   

TargetSteroid hormone receptor ERR1 LBD(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97124BDBM97124((R)-3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchrom...)
Affinity DataIC50: 5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97124BDBM97124((R)-3-(1'-((2-(4-((3R,4S)-7-hydroxy-3- phenylchrom...)
Affinity DataIC50: 50nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent