BDBM97447 Aspartyl protease inhibitor, 13

SMILES CC(C)CN(C[C@@H]1C[NH2+]CC1CN(Cc1ccccc1)C(=O)COc1c(C)cccc1C)S(=O)(=O)c1ccccc1

InChI Key InChIKey=MQRMHPRUUKDEKO-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97447   

TargetGag-Pol polyprotein(HIV-1)
Philipps-Universität Marburg

LigandPNGBDBM97447(Aspartyl protease inhibitor, 13)
Affinity DataIC50: 2.20E+3nMpH: 5.5Assay Description:Binding constants for inhibition of HIV protease were determined as previously described.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2013
Entry Details Article
PubMed
TargetCathepsin D(Human)
Philipps-Universität Marburg

LigandPNGBDBM97447(Aspartyl protease inhibitor, 13)
Affinity DataIC50: 4.00E+4nMpH: 5.5Assay Description:Binding constants for inhibition of HIV protease were determined as previously described.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2013
Entry Details Article
PubMed