BDBM97581 US8470836, 8
SMILES N[C@H](CN1[C@@H](O)C(F)(F)CCC1=O)CC(=O)N1CCc2c(C1)nc(nc2C(F)(F)F)-c1ccco1
InChI Key InChIKey=QGMCXZMURXFXMP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 97581
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Enzymatic reactions were conducted for various concentrations of inhibitors, using 100 μM Ac-Gly-Pro-AFC at 25° C. in a buffer solution contai...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMpH: 4.5 T: 2°CAssay Description:Enzymatic reactions were conducted for various concentrations of DPP-IV inhibitors, using 0.018 μg DPP-II and 100 μM Gly-Pro-AFC in a buffer so...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+5nMpH: 7.5 T: 2°CAssay Description:DPP-IX was obtained and purified. Using Gly-Pro-AFC as the substrate, DPP-IV inhibitors as set forth in Table 2 below were assayed for DPP-IX inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+5nMpH: 7.5 T: 2°CAssay Description:DPP-VIII was obtained and purified. Using Gly-Pro-AFC as the substrate, DPP-IV inhibitors as set forth in Table 2 below were assayed for DPP-VIII inh...More data for this Ligand-Target Pair