BDBM98297 US8481733, 109

SMILES C[C@@]1(O)C[C@@H](C1)c1nc(-c2ccc(cc2F)C(=O)c2ccccc2)c2c(N)nccn12

InChI Key InChIKey=SZXPNKVJYHCENL-ONEIWYMKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 98297   

TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98297(US8481733, 109)
Affinity DataIC50:  88.6nMAssay Description:AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98297(US8481733, 109)
Affinity DataIC50:  88nMAssay Description:Inhibition of ACK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98297(US8481733, 109)
Affinity DataIC50:  28nMAssay Description:Inhibition of ACK1 (unknown origin) by cellular mechanistic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed