BDBM99463 BDBM327953::US8497281, 241

SMILES Cc1cc2c(cc1C#N)[C@H]1CCCN(C(=O)c3ccc4nc[nH]c4c3)[C@H]1C2

InChI Key InChIKey=WAGZLEPKWTWONO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99463   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 99463BDBM99463(US8497281, 241 | BDBM327953)
Affinity DataIC50: 3.60nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 99463BDBM99463(US8497281, 241 | BDBM327953)
Affinity DataIC50: 58.4nMAssay Description:In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 99463BDBM99463(US8497281, 241 | BDBM327953)
Affinity DataIC50: 67nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
US Patent