BDBM9955 (8S)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-one::6-Substituted Androst-4-ene Analog 18a

SMILES C[C@H]1CC2C3CCC(=O)C3(C)CCC2C2(C)CCCC=C12

InChI Key InChIKey=SPQYFKZBWJXPTC-VBDFFWHESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9955   

TargetAromatase(Human)
Tohoku College of Pharmacy

LigandPNGBDBM9955((8S)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{1...)
Affinity DataKi:  3.10nM ΔG°:  -12.1kcal/mole IC50:  37nMpH: 7.5 T: 37°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed