BDBM99573 US8501936, 71

SMILES CN1CCN(CC1)c1cccc(Nc2nc3cccc(-c4ccc(CN5CCS(=O)(=O)CC5)cc4)n3n2)c1

InChI Key InChIKey=NPELBSOBEYYYKY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99573   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

US Patent
LigandPNGBDBM99573(US8501936, 71)
Affinity DataIC50: 0.800nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Cephalon

US Patent
LigandPNGBDBM99573(US8501936, 71)
Affinity DataIC50: 37.8nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Cephalon

US Patent
LigandPNGBDBM99573(US8501936, 71)
Affinity DataIC50: 502nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent