BDBM99586 US8501936, 85

SMILES CS(=O)(=O)c1ccc(cc1)-c1cccc2nc(Nc3ccc(CN4CCOCC4)cc3)nn12

InChI Key InChIKey=XCJNPYULTYFKFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99586   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

US Patent
LigandPNGBDBM99586(US8501936, 85)
Affinity DataIC50: 1.10nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Cephalon

US Patent
LigandPNGBDBM99586(US8501936, 85)
Affinity DataIC50: 36.8nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Cephalon

US Patent
LigandPNGBDBM99586(US8501936, 85)
Affinity DataIC50: 173nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent