BDBM9986 (2S,6R,15S)-2-(hydroxymethyl)-15-methyl-14-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-6-yl acetate::4alpha-Acetoxy-19-hydroxyandrost-5-en-17-one::Hydroxylated 3-Deoxy C19 Steroid 21

SMILES CC(=O)O[C@@H]1CCC[C@]2(CO)C3CC[C@@]4(C)C(CCC4=O)C3CC=C12

InChI Key InChIKey=VSJZHRQZVXIRAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9986   

TargetAromatase(Human)
Tohoku Pharmaceutical University

LigandPNGBDBM9986((2S,6R,15S)-2-(hydroxymethyl)-15-methyl-14-oxotetr...)
Affinity DataIC50: 1.10E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2006
Entry Details Article
PubMed