BDBM85484 Bombesin

SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCC(=O)N1)C(C)C)C(N)=O

InChI Key InChIKey=QXZBMSIDSOZZHK-DOPDSADYSA-N

Data  12 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 85484   

TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  0.150nMAssay Description:In vitro binding affinity at Bombesin BB2 receptor in the presence of [125I]-[Tyr] bombesin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  0.150nMAssay Description:Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human GRP(gastrin releasing peptide) receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin-releasing peptide receptor(MOUSE)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  1.24nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(MOUSE)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  1.31nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(MOUSE)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  1.32nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(MOUSE)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  1.76nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  2nMAssay Description:Antagonism of recombinant human bombesin receptor (bb1) labeled with [125I]- [Tyr] bombesin stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-B receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  2nMAssay Description:Binding affinity against [125 I][4Tyr]-bombesin labeled cloned human NMB receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGastrin-releasing peptide receptor(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM85484(Bombesin)
In DepthDetails ArticlePubMed
TargetBombesin(Frog)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-B receptor(RAT)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM85484(Bombesin)
Affinity DataKi:  34nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM85484(Bombesin)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [125I]-NPY from Y1 receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]-Tyr4-BBN from human GRPR overexpressed in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGastrin-releasing peptide receptor(Homo sapiens (Human))
Cambridge University Forvie Site

Curated by ChEMBL
LigandPNGBDBM85484(Bombesin)
Affinity DataEC50:  0.258nMAssay Description:Displacement of 125I[Tyr4]-bombesin from GRPR expressed in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed