BDBM50003659 5H-dibenzo[b,f]azepine-5-carboxamide::CARBAMAZEPINE::CARBATROL::CHEMBL108::DIBENZO[B,F]AZEPINE-5-CARBOXYLIC ACID AMIDE(CARBAMAZEPINE)::EPITOL::EQUETRO::G-32883::TEGRETOL::TEGRETOL-XR::TERIL::US9138393, Carbamazepine::US9144538, Carbamazepine
SMILES NC(=O)N1c2ccccc2C=Cc2ccccc12
InChI Key InChIKey=FFGPTBGBLSHEPO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 36 hits for monomerid = 50003659
Affinity DataKi: 3.27E+4nMAssay Description:Inhibition of Nav1.7 (unknown origin) by electrophysiological assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 5.20E+4nMAssay Description:Affinity for inactive human SkM1 sodium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+5nMAssay Description:Displacement of [3H]batrachotoxin A 20alpha-benzoate (BTX-B) from rat cerebral cortex voltage-gated sodium channelMore data for this Ligand-Target Pair
Affinity DataIC50: 1.67E+5nMAssay Description:Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+5nMAssay Description:In vitro inhibition of [3H]-BTX-B binding to sodium channels in rat brain synapto-neurosomesMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in ratsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+5nMAssay Description:Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomesMore data for this Ligand-Target Pair
Affinity DataEC50: 1.45E+5nMAssay Description:Induction of CYP2B6 activity in human donor hepatocytes assessed as hydroxybupropion formation after 48 hrs by LC/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+5nMAssay Description:In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...More data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+5nMAssay Description:Inhibition of [3H]BTX-B binding to neurotoxin site 2 of sodium channel of rat cerebral cortex synaptoneurosomesMore data for this Ligand-Target Pair
Affinity DataKd: 1.68E+4nMAssay Description:Binding affinity to immobilized mouse C-terminal Rhinovirus 3C cleavage site-fused 6xHis-tagged Frizzled-8 CRD (Q33 to G173 resideus) transfected wit...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 4.68E+4nMAssay Description:Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Blockade of human Nav1.7 channel expressed in HEK293 cells by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.13E+4nMAssay Description:Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.03E+5nMAssay Description:Binding affinity to Wistar rat serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair