BDBM86848 1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)urea::CAS_16041629::NSC_16041629

SMILES CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)NC(=O)Nc1cc(F)ccc1F

InChI Key InChIKey=NXJNUASOAQRPKJ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 86848   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86848(1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  0.460nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86848(1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86848(1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  1.70nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86848(1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  26nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86848(1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  36.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86848(1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  52nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86848(1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  199nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM86848(1-(2,5-difluorophenyl)-3-(4-(4-(2-isopropoxyphenyl...)
Affinity DataKi:  259nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed