BDBM50379186 CEP-11981::CHEMBL2010872
SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12
InChI Key InChIKey=AEULIVPVIDOLIN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 27 hits for monomerid = 50379186
Affinity DataKi: 500nMAssay Description:Inhibition of adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Inhibition of muscarinic M4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Erg expressed CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human TRK-B using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human TRK-A using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human TAK1 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human RET using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 246nMAssay Description:Inhibition of human PDGFRalpha using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human MST2 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of human FMS using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of human FLT3 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human VEGFR1 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of human FGFR3 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human FGFR1 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human cSrc using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of CK1 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human CHK2 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human BTK using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human Aurora-A using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of human ALK using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human Tie2 expressed in porcine PAE145 cells cotransfected with chimeric rat TRK-A/KDR receptor after 1 hr by immunofluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse BLK using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...More data for this Ligand-Target Pair