BDBM50413999 CGP77675::CHEMBL475584
SMILES COc1cccc(c1)-c1cn(-c2ccc(CCN3CCC(O)CC3)cc2)c2ncnc(N)c12
InChI Key InChIKey=WUPXZZWTHIZICK-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50413999
Affinity DataIC50: 0.400nMT: 2°CAssay Description:Kinase activity (Src-family kinases, Hck, Lyn, Fyn, and c-Src) and the effect of the molecules were determined by ProFluor Src-Family Kinase Assay Ki...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant His-tagged EGFR expressed in baculovirus using poly-Gluo-Tyr as a substrate measured after 24 hrs by western blot ana...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of c-Src kinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Src kinase (unknown origin) phosphorylation at Tyr416/419 residues incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Indo-Soviet Friendship College of Pharmacy (Isfcp)
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Lyn (unknown origin) using Src-family kinase bisamide rhodamine 110 peptide substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair