BDBM50053822 CHEMBL132586::Calpain XII::{3-Methyl-1-[1-(pyridin-2-ylmethyl)-aminooxalyl]-butylcarbamoyl}-butyl)-carbamic acid benzyl ester

SMILES CCCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCc1ccccn1

InChI Key InChIKey=PLVWMBFPIAQRHK-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50053822   

TargetCalpain-1 catalytic subunit(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50053822(CHEMBL132586 | Calpain XII | {3-Methyl-1-[1-(pyrid...)
Affinity DataKi:  19nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50053822(CHEMBL132586 | Calpain XII | {3-Methyl-1-[1-(pyrid...)
Affinity DataKi:  120nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50053822(CHEMBL132586 | Calpain XII | {3-Methyl-1-[1-(pyrid...)
Affinity DataKi:  750nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50053822(CHEMBL132586 | Calpain XII | {3-Methyl-1-[1-(pyrid...)
Affinity DataIC50:  450nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50053822(CHEMBL132586 | Calpain XII | {3-Methyl-1-[1-(pyrid...)
Affinity DataEC50:  490nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed