BDBM50051942 CHEMBL3322563
SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1
InChI Key InChIKey=LILXUVCZUBSSFA-ZDLGFXPLSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50051942
Affinity DataIC50: 552nMAssay Description:Inhibition of Aurora A (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of Aurora C (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Human)
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair