BDBM50051942 CHEMBL3322563

SMILES Fc1ccc(NC(=O)CC(=O)Nc2ccc3\C(=C\c4ccc[nH]4)C(=O)Nc3c2)cc1

InChI Key InChIKey=LILXUVCZUBSSFA-ZDLGFXPLSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50051942   

TargetAurora kinase A(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051942(CHEMBL3322563)
Affinity DataIC50:  552nMAssay Description:Inhibition of Aurora A (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051942(CHEMBL3322563)
Affinity DataIC50:  25nMAssay Description:Inhibition of Aurora B (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051942(CHEMBL3322563)
Affinity DataIC50:  67nMAssay Description:Inhibition of Aurora C (unknown origin) using H-LRRASLG substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051942(CHEMBL3322563)
Affinity DataIC50:  11nMAssay Description:Inhibition of Flt3 (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051942(CHEMBL3322563)
Affinity DataIC50:  87nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051942(CHEMBL3322563)
Affinity DataIC50:  1.77E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly[Glu:Tyr] substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50051942(CHEMBL3322563)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of PDGFRalpha (unknown origin) using EAIYAAPFAKKK substrate by radioisotope-based P81 filter-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed