BDBM50270018 CHEMBL4075205

SMILES C(NC1CCOCC1)\C=C\CN(C[C@H]1Cc2ccccc2CN1)[C@H]1CCCc2cccnc12

InChI Key InChIKey=QPAGOTNPJABYCP-FITNPZAZSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50270018   

TargetCytochrome P450 3A4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50:  7.73E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50: <5.00E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataEC50: >3.00E+4nMAssay Description:Antagonist activity at human CXCR4 in CCRF-CEM cells assessed as decrease in SDF-1alpha stimulated Ca2+ flux preincubated for 25 mins followed by SDF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50:  2.61E+3nMAssay Description:Inhibition of recombinant human CYP2D6 expressed in microsomes of insect cells using AMMC as substrate preincubated for 30 mins followed by NADP addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50: <5.00E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50: <5.00E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Mouse)
Emory University

Curated by ChEMBL
LigandPNGBDBM50270018(CHEMBL4075205)
Affinity DataIC50:  9.20nMAssay Description:Antagonist activity at mouse CXCR4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed