BDBM50011527 CHEMBL2396783

SMILES [Na+].CCOC(=O)c1c(C)oc2cc(OC)c(OCc3oc4cc(OC)c(OCc5oc6cc(OC)c(OS([O-])(=O)=O)cc6c5C(=O)OCC)cc4c3C(=O)OCC)cc12

InChI Key InChIKey=HFRQXCHDKWDRKU-UHFFFAOYSA-M

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50011527   

TargetCoagulation factor XI(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011527(CHEMBL2396783)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011527(CHEMBL2396783)
Affinity DataIC50:  263nMAssay Description:Inhibition of wild type recombinant human thrombin expressed in BHK cells using S2238 as substrate after overnight incubation at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011527(CHEMBL2396783)
Affinity DataIC50:  370nMAssay Description:Inhibition of recombinant human thrombin R97A mutant expressed in BHK cells using S2238 as substrate after overnight incubation at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011527(CHEMBL2396783)
Affinity DataIC50:  363nMAssay Description:Inhibition of recombinant human thrombin R97A mutant expressed in BHK cells using S2238 as substrate after overnight incubation at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011527(CHEMBL2396783)
Affinity DataIC50:  260nMAssay Description:Inhibition of wild type recombinant human thrombin expressed in BHK cells using S2238 as substrate after overnight incubation at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed