BDBM50011525 CHEMBL2396787

SMILES [Na+].CCOC(=O)c1c(C)oc2cc(OC)c(OCc3oc4cc(OC)c(OCc5oc6cc(OCC)c(OS([O-])(=O)=O)cc6c5C(=O)OCC)cc4c3C(=O)OCC)cc12

InChI Key InChIKey=CWMXHCYBMZHUFV-UHFFFAOYSA-M

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50011525   

TargetCoagulation factor XI(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011525(CHEMBL2396787)
Affinity DataIC50:  820nMAssay Description:Inhibition of full-length human factor-11a-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotometric a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011525(CHEMBL2396787)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of human factor-11a catalytic domain-mediated S-2366 hydrolysis preincubated for 10 mins followed by substrate addition by spectrophotomet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50011525(CHEMBL2396787)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to fluorescein-EGR-labeled human factor-11a by fluorescence spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed