BDBM50026677 CHEMBL3335377

SMILES CCc1ccc(Nc2nc3cc(Oc4ccnc(NC(C)=O)c4)ccc3n2C)cc1

InChI Key InChIKey=ZVLQDFZYWZFDCF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50026677   

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026677(CHEMBL3335377)
Affinity DataIC50:  1nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50026677(CHEMBL3335377)
Affinity DataEC50:  80nMAssay Description:Inhibition of BRAF (unknown origin)-mediated ERK phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed