BDBM50523811 CHEMBL2094331::DNDI1416941

SMILES O=C1Nc2ccccc2\C1=C\c1ccccn1

InChI Key InChIKey=YKQONSWBHGBDSB-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523811   

TargetGlycogen synthase kinase-3 beta(Human)
Lomonosov Moscow State University

Curated by ChEMBL

LigandBDBM50523811(DNDI1416941 | CHEMBL2094331)Copy SMILESCopy InChI

Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human GSK3beta using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate measured after 60 mins by ADP-Glo luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

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In Depth
Date in BDB:
2/24/2021
Entry Details Article
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TargetSerine/threonine-protein kinase tousled-like 2(Human)TBA

LigandBDBM50523811(DNDI1416941 | CHEMBL2094331)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TLK2 preincubated for 20 mins followed by 33P-ATP addition and measured after 120 mins by hotspot assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

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In Depth
Date in BDB:
TBA
Entry Details
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