BDBM50510823 E-2609::E2609::Elenbecestat

SMILES [H][C@]12CSC(N)=N[C@]1(CO[C@@H]2C)c1cc(NC(=O)c2cnc(cn2)C(F)F)ccc1F

InChI Key InChIKey=AACUJFVOHGRMTR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510823   

TargetBeta-secretase 1(Human)
University of Turin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510823BDBM50510823(E-2609 | E2609 | Elenbecestat)
Affinity DataKi:  27nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
University of Turin

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50510823BDBM50510823(E-2609 | E2609 | Elenbecestat)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant BACE1 (unknown origin) using H-Ile-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-NH2 as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed