BDBM50661662 Centanafadina::Centanafadine::DOV 216,419::DOV 216,419 free base::DOV-216419::EB-1020::EB-1020 free base

SMILES c1ccc2cc([C@]34CNC[C@H]3C4)ccc2c1

InChI Key InChIKey=HKHCSWPSUSWGLI-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50661662   

TargetSodium-dependent noradrenaline transporter(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661662BDBM50661662(Centanafadine | Centanafadina | DOV 216,419 | DOV ...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661662BDBM50661662(Centanafadine | Centanafadina | DOV 216,419 | DOV ...)
Affinity DataIC50: 60nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50661662BDBM50661662(Centanafadine | Centanafadina | DOV 216,419 | DOV ...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed