BDBM50129950 EBSELEN

SMILES O=c2c1ccccc1[se]n2c3ccccc3

InChI Key InChIKey=DYEFUKCXAQOFHX-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50129950   

TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of SARS-CoV-2 MPro using Dabcyl-KTSAVLQSGFRKME-Edans as substrate preincubated for 30 mins followed by substrate addition measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant SARS-CoV2 6xHis-tag-Main protease containing modified HRV-3C expressed in Escherichia coli using Mca-AVLQSGFR-K(Dnp)K pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCysteine protease ATG4B(Human)
China Jiliang University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 180nMAssay Description:Inhibition of ATG4B (unknown origin) using pim-FG-PABA-AMC as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant SARS CoV-2 main protease by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataKi:  380nMAssay Description:Inhibition of NDM-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Baylor College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 705nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using Dabcyl-KTSAVLQSGFRKME-Edans as fluorogenic substrate pre-incubated with compound for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Connecticut

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of YTHDC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing family protein 1(Human)
University of Connecticut

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of YTHDF1 (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
Palacky University Olomouc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Palacky University Olomouc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129950BDBM50129950(EBSELEN)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed