BDBM50262797 2-(4-trifluoromethyphenyl)ethylamine::CHEMBL478405::EN300-34269

SMILES NCCc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HMFOBPNVAAAACP-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262797   

TargetTrace amine-associated receptor 1(Homo sapiens (Human))
Rti International

Curated by ChEMBL
LigandPNGBDBM50262797(2-(4-trifluoromethyphenyl)ethylamine | CHEMBL47840...)
Affinity DataEC50:  1.16E+4nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50262797(2-(4-trifluoromethyphenyl)ethylamine | CHEMBL47840...)
Affinity DataIC50:  77nMAssay Description:IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50262797(2-(4-trifluoromethyphenyl)ethylamine | CHEMBL47840...)
Affinity DataIC50:  110nMAssay Description:IC50 values were determined using 12 point 2-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50262797(2-(4-trifluoromethyphenyl)ethylamine | CHEMBL47840...)
Affinity DataIC50:  5.57E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In DepthDetails PubMed