BDBM225922 FXR_11

SMILES O=C1N(Cc2ccc(-c3nnn[nH]3)cc2)c2ccc(Br)cc2C12CCN(S(=O)(=O)c1cccs1)CC2

InChI Key InChIKey=PDMCUTCDLHMYSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225922   

TargetBile acid receptor(Human)
D3R/Abbott

LigandChemical structure of BindingDB Monomer ID 225922BDBM225922(FXR_11)
Affinity DataIC50: 120nMpH: 7.4Assay Description:The assay buffer contained 50 mM HEPES (pH 7.4), 10 mM NaCl, 5 mM MgCl2 and 0.01% CHAPS. The reactions were incubated for 30 min in the presence of [...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R