BDBM50622531 CHEBI:38562::FLUVASTATIN::Fluvas::Fluvastatin::Fluvastatina::Fluvastatine::NSC-758896

SMILES CC(C)n1c(\C=C\C(O)CC(O)CC(O)=O)c(-c2ccc(F)cc2)c2ccccc12

InChI Key InChIKey=FJLGEFLZQAZZCD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622531   

TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50622531(CHEBI:38562 | Fluvastatin | Fluvastatine | Fluvast...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human Nurr1 transfected in HEK293T cells co-transfected with pFR-Luc/pRL-SV40/pFA-CMV-hNurr1-LBD assessed as luciferase activity ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig Maximilian University of Munich

Curated by ChEMBL
LigandPNGBDBM50622531(CHEBI:38562 | Fluvastatin | Fluvastatine | Fluvast...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at Gal4-fused human full length Nurr1 transfected in human HEK293T cells co-transfected with pFR-Luc/pRL-SV40 assessed as activation...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed