BDBM50415291 CHEMBL605836::GSK-1331258
SMILES Cn1c(CN2CCN(CC2)c2ncc(cc2Cl)C(F)(F)F)nc2ccccc12
InChI Key InChIKey=BQOUGDGGUWVLTD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50415291
Affinity DataKi: 631nMAssay Description:Antagonist activity at human D4 receptor expressed in HEK293 cells co-expressing Gqo5 G-protein by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.01E+3nMAssay Description:Antagonist activity at human D2 receptor expressed in CHO cells co-expressing G0 by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.01E+3nMAssay Description:Antagonist activity at human D3 receptor expressed in CHO cells co-expressing G0 by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 79.4nMAssay Description:Positive modulation of human mGluR2 expressed in CHO cells co-expressing Ga16 G-protein assessed as glutamate-induced response by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human mGluR2 expressed in CHO cells co-expressing Ga16 G-protein assessed as glutamate-induced response by FLIPR assayMore data for this Ligand-Target Pair