BDBM23413 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one::Apigenin-7,4'-dimethylether::Genkwanin::apigenin dimethylether

SMILES COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC)cc2o1

InChI Key InChIKey=LZERJKGWTQYMBB-UHFFFAOYSA-N

Data  2 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23413   

TargetAlpha-amylase 1A(Human)
Nestle Research Center

LigandPNGBDBM23413(5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen...)
Affinity DatapH: 6.0 T: 22°CAssay Description:The assay was carried out at room temperature for 10 min with salivary alpha-amylase, starch, and test compounds. The reducing sugar was determined b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM23413(5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen...)
Affinity DataIC50:  198nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Eberhard Karls University of Tuebingen

LigandPNGBDBM23413(5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen...)
Affinity DataIC50:  2.78E+4nMT: 37°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed