BDBM50663477 ABBV-2222::GLPG-2222::GLPG2222::Galicaftor::Glpg2222

SMILES O=C(O)c1ccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c3ccc(OC(F)F)cc3O2)cc1

InChI Key InChIKey=QVDYQHXNAQHIKH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50663477   

LigandChemical structure of BindingDB Monomer ID 50663477BDBM50663477(Galicaftor | Glpg2222 | ABBV-2222 | GLPG-2222 | GL...)
Affinity DataEC50:  5nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in HBE cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed