BDBM50458916 Grifolin
SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#6])cc1-[#8]
InChI Key InChIKey=PZHNKNRPGLTZPO-VZRGJMDUSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50458916
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant human PTP1B catalytic domain (91 to 1053 residues) expressed in Escherichia coli BL21-codon plus (DE3) using pNPP as substr...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Meiji Pharmaceutical University
Curated by ChEMBL
Meiji Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Meiji Pharmaceutical University
Curated by ChEMBL
Meiji Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of human amyloid beta (1 to 40) aggregation after 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair