BDBM2737 3,4-dihydroquinoxaline-2(1H)-thione derivative::HBY-097::propan-2-yl (2S)-7-methoxy-2-[(methylsulfanyl)methyl]-3-sulfanylidene-1,2,3,4-tetrahydroquinoxaline-1-carboxylate

SMILES COc1ccc2NC(=S)[C@H](CSC)N(C(=O)OC(C)C)c2c1

InChI Key InChIKey=GWKIPRVERALPRD-ZDUSSCGKSA-N

Data  3 IC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2737   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2737(3,4-dihydroquinoxaline-2(1H)-thione derivative | H...)
Affinity DataIC50:  8nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2737(3,4-dihydroquinoxaline-2(1H)-thione derivative | H...)
Affinity DataIC50:  56nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Medivir

LigandPNGBDBM2737(3,4-dihydroquinoxaline-2(1H)-thione derivative | H...)
Affinity DataIC50:  9nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair