BDBM50659304 HEMAY-005::HEMAY005::Mufemilast

SMILES CCOc1cc([C@@H](CS(C)(=O)=O)N2C(=O)c3csc(NC(C)=O)c3C2=O)ccc1OC

InChI Key InChIKey=PRSNGWLHNWGOKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50659304   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Wuyi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659304BDBM50659304(Mufemilast | HEMAY-005 | HEMAY005)
Affinity DataIC50: 114nMAssay Description:Inhibition of PDE4D (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Southern Medical University (The First People's Hospital of Shunde)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659304BDBM50659304(Mufemilast | HEMAY-005 | HEMAY005)
Affinity DataIC50: 114nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed