BDBM50241641 (+)-Homoaromoline::CHEMBL509855::Homoaromoline::Limacusine (R,S)

SMILES COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(Oc5c(O)c(OC)cc6CCN(C)[C@@H](Cc7ccc(Oc1c2)cc7)c56)cc34

InChI Key InChIKey=YJRWQNIRFXVBRB-WDYNHAJCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241641   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50241641((+)-Homoaromoline | CHEMBL509855 | Homoaromoline |...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50241641((+)-Homoaromoline | CHEMBL509855 | Homoaromoline |...)
Affinity DataIC50:  5.50E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed