BDBM50293282 CHEMBL504535::Imrecoxib
SMILES CCCN1CC(=C(C1=O)c1ccc(C)cc1)c1ccc(cc1)S(C)(=O)=O
InChI Key InChIKey=AXMZZGKKZDJGAZ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50293282
Affinity DataIC50: 18nMAssay Description:Inhibition of LPS-induced COX-2 in peritoneal macrophage of C57BL/J6 mouse assessed as prostaglandin E2 formation preincubated for 1 hr followed by L...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Mus musculus)
Chinese Academy Of Medical Sciences
Curated by ChEMBL
Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 114nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of COX2 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Mus musculus)
Chinese Academy Of Medical Sciences
Curated by ChEMBL
Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of calcimycin-induced COX-1 in peritoneal macrophage of C57BL/J6 mouse assessed as 6-Keto prostaglandin F1alpha formation preincubated for...More data for this Ligand-Target Pair