BDBM50014210 1-(1H-Indol-3-yl)-2-propanamine::1-(1H-indol-3-yl)propan-2-amine::3-(2-Aminopropyl)indole::CHEMBL30713::DL-3-(2-Aminopropyl)indole::Indopan::alpha-Methyl-1H-indole-3-ethanamine::alpha-Methyl-3-indoleethanamine::alpha-Methyl-beta-indoleethylamine::alpha-methyltryptamine

SMILES CC(N)Cc1c[nH]c2ccccc12

InChI Key InChIKey=QSQQQURBVYWZKJ-UHFFFAOYSA-N

Data  12 KI  4 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50014210   

Target5-hydroxytryptamine receptor 1A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi:  530nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Human)
Ucl School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha4beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H1 receptor(Human)
Ucl School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H2 receptor(Human)
Ucl School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Tiotidine from human recombinant histamine H2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Ucl School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Pentazocine from guinea pig sigma 1 receptor after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Ucl School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D2 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 3A(Human)
Ucl School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LY278584 from human recombinant 5-HT3 receptor expressed in HEK293T cells after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Ucl School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from alpha4beta2 nACh receptor in HEK293 cells after 1 to 1.5 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Ucl School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha4beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha2beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha2beta2 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataEC50:  79nMAssay Description:Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataEC50:  112nMAssay Description:Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)
Affinity DataEC50:  22nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed