BDBM716452 JAK315::US20250034112, Compound 11
SMILES Nc1nc(Oc2ccc(CC(=O)C[C@@H](CCc3ccccc3)C(=O)O)cc2)c2cc[nH]c2n1
InChI Key InChIKey=GWQCKLGDCHSZKC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 716452
Affinity DataIC50: 33nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Affinity DataKd: 37.1nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Affinity DataIC50: 37.1nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Affinity DataIC50: 327nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Affinity DataKd: 327nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Affinity DataKd: 327nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Affinity DataIC50: 5.75E+3nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+4nMAssay Description:Binding affinities (Kd) with the JAK2 JH2 domain were evaluated using the previously developed FP assay and compound 1 as a control. An initial scree...More data for this Ligand-Target Pair