BDBM532291 JDM0443A::N-[1-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]-3,5-dimethyl-pyrazol-4-yl]-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide::US11208696, Example 10

SMILES COCCOCCOCCn1nc(C)c(NC(=O)c2ccn-3c2CCc2cnc(Nc4ccc(cc4OC)N4CCN(C)CC4)nc-32)c1C

InChI Key InChIKey=UFIJTGYZCFZMPA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 532291   

TargetDual specificity protein kinase TTK(Human)
Netherlands Translational Research Center

US Patent
LigandPNGBDBM532291(JDM0443A | N-[1-[2-[2-(2-methoxyethoxy)ethoxy]ethy...)
Affinity DataIC50: 0.930nMAssay Description:The inhibitory activity of compounds on biochemically purified full-length TTK (Life Technologies, Madison, Wis., U.S.A.) was determined in the IMAP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent