BDBM36513 CID46912128::KY170, 4::US9056847, Azido-cyclophellitol

SMILES O[C@H]1[C@@H]2O[C@@H]2[C@H](CN=[N+]=[N-])[C@@H](O)[C@@H]1O

InChI Key InChIKey=ZESQJCJZDKDCAM-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36513   

TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM36513(CID46912128 | KY170, 4 | US9056847, Azido-cyclophe...)
Affinity DataKi:  44nM ΔG°:  -10.4kcal/mole IC50: 120nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandPNGBDBM36513(CID46912128 | KY170, 4 | US9056847, Azido-cyclophe...)
Affinity DataKi:  83nM IC50: 150nMpH: 5.2Assay Description:Activity of GBA was measured at 37° C. with 4-methylumbelliferyl β-D-glucopyranoside as substrate as reported previously. To determine the IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent