BDBM81975 4-hydroxyquinoline-2-carboxylic acid::CAS_492-27-3::CHEMBL299155::Kynurenate::NSC_5280455
SMILES OC(=O)c1cc(O)c2ccccc2n1
InChI Key InChIKey=HCZHHEIFKROPDY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 81975
Affinity DataKi: 5.40E+3nMAssay Description:Tested for the ability to displace [3H]-glycine, by greater than 50%, from NMDA receptor of rat cortical membranes at a dose of 10 microMMore data for this Ligand-Target Pair
Affinity DataKi: 5.40E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 1.37E+5nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+6nMAssay Description:Compound was evaluated for the inhibition of Vesicular glutamate transporter (VGLUT)More data for this Ligand-Target Pair
Affinity DataEC50: 6.60E+4nMAssay Description:Agonist activity at rat GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.52E+5nMAssay Description:Agonist activity at GPR35 in human HT-29 cells by dynamic mass redistribution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of alpha7 nAChR (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Activation of AHR (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.17E+5nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
Affinity DataEC50: 1.52E+5nMAssay Description:Agonist activity at human GPR35 by DMR assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+5nMAssay Description:Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and Gal4-VP16 transcription factor assessed as beta arrestin translocation af...More data for this Ligand-Target Pair
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
Affinity DataEC50: 3.92E+4nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as increase in intracellular Ca2+ measured over 20 secs by Aequorin assayChecked by AuthorMore data for this Ligand-Target Pair