BDBM50281848 2-Ethyl-5,7-dimethyl-3-{4-[2-(2H-tetrazol-5-yl)-5H-1lambda*4*-thiophen-3-yl]-benzyl}-3H-imidazo[4,5-b]pyridine::2-Ethyl-5,7-dimethyl-3-{4-[2-(2H-tetrazol-5-yl)-thiophen-3-yl]-benzyl}-3H-imidazo[4,5-b]pyridine::CHEMBL58156::L-158827

SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccsc1-c1nnn[nH]1

InChI Key InChIKey=XPAQGRYPYVGJTN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50281848   

LigandPNGBDBM50281848(L-158827 | 2-Ethyl-5,7-dimethyl-3-{4-[2-(2H-tetraz...)
Affinity DataIC50: 2.30nMAssay Description:Compound was tested for inhibition of Angiotensin II receptor in rabbit aorta binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2018
Entry Details

TargetType-2 angiotensin II receptor(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50281848(L-158827 | 2-Ethyl-5,7-dimethyl-3-{4-[2-(2H-tetraz...)
Affinity DataIC50: 2.30nMAssay Description:Binding affinity to angiotensin AT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50281848(L-158827 | 2-Ethyl-5,7-dimethyl-3-{4-[2-(2H-tetraz...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Angiotensin II receptor type 1 in rabbit aorta binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50281848(L-158827 | 2-Ethyl-5,7-dimethyl-3-{4-[2-(2H-tetraz...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rat midbrain angiotensin II type 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article