BDBM50292408 (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)glycine::5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoic acid::CHEMBL288943::LTD4::S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycine::leukotriene D4

SMILES CCCCC\C=C/C\C=C/C=C/C=C/[C@@H](SC[C@H](N)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O

InChI Key InChIKey=YEESKJGWJFYOOK-IJHYULJSSA-N

Data  6 KI  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50292408   

TargetDipeptidase 1(Pig)
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataKi:  0.490nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetCysteinyl leukotriene receptor 2(Guinea pig)
Pfizer

Curated by PDSP Ki Database
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataKi:  0.490nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetCysteinyl leukotriene receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]LTD4 from LTD4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLeukotriene B4 receptor 2(Human)
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataKi:  3.48nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLeukotriene B4 receptor 1(Human)
Schering-Plough Research Institute

Curated by PDSP Ki Database
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataKi:  4.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLeukotriene B4 receptor 2(Human)
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human leukotriene D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetATP-binding cassette sub-family C member 2(Rat)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataIC50:  5.48E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake (E217betaG: 0.055 uM) in membrane vesicles from Mrp2-expressing Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human CysLT1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCysteinyl leukotriene receptor 2(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human CysLT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed